Joseph E. LeDoux (born 7 December 1949, Eunice, Louisiana) is a neuroscientist, the Henry and Lucy Moses Professor of Science, and professor of neuroscience and psychology at New York University. He is also the director of the Center for the Neuroscience of Fear and Anxiety, a multi-university Center in New York City devoted to using animal research to understand pathological fear and anxiety in humans. He received his Ph.D. in 1977 at the State University of New York at Stony Brook. He was a recipient of the 2005 International Prize of the Fyssen Foundation. LeDoux's research interests are mainly focused on the biological underpinnings of memory and emotion, especially the mechanisms of fear.
LeDoux is also a singer and guitarist in the science-themed rock band The Amygdaloids.